Duct tape works great, especially for the nipples....it's not really that bad taking it off, but works great as a barrier while running. I have considered body glide before, and I have used vaseline, which worked OK, but duct tape is the cats ass!
I agree on the obesity topic. I have been there before; I got married in August 2003, two months after completing my bachelor of civil engineering, and I was 265 lbs (I am only 5'-10"). I was much more of the power lifter type in my college days and was actually fairly strong (example, bench press = 375 lbs, squat = 550 lbs). I yo-yo'd around between 225 and 260 from 2003 until early 2008, when I decided I needed to change. Then, in about 6 months I dropped my weight down to 180 lbs, and in 2009, started my running hobby.
So as someone who has been among the obese, and now NOT, I can't even put into words how much better I feel day in and day out now than I did for all those years. I remember something as simple as running up one flight of steps at the office and being almost out of breath. Now doing that only slightly raises the heart rate, and it recovers almost instantly.